Protein Details: Potassium voltage-gated channel subfamily E member 4
Protein ID
ICDB_Pro_1691
Protein Name
Potassium voltage-gated channel subfamily E member 4
Gene Name
Kcne4
Organism
Mus musculus (Mouse)
Length
170 amino acids
AlphaFoldDB
AF-Q9WTW3-F1-model_v4.pdb
Function
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 and inhibits potassium currents. May also inhibit KCNQ4-mediated potassium currents
Sequence
MLRMEPLNSTYPSAAASSSPLESHVPSNSSGNGNEYFYILVVMSFYGVFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMKPLPMMSGLRSGQVPMMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLPIQEEGADDELEETSETPLNDSSEGSSENIHQNS
PDB Structures
Ligand Binding
Binding Site
Disease
Location
DOI ID
10.1101/gr.2596504
RefSeq
NP_067317.1